Mixed leukocyte reactivity and leukemia: study of identical siblings

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Mixed leukocyte reactivity and leukemia: study of identical siblings.

This report describes a search for tumor-specific transplantation antigens in man by testing four sets of identical siblings using the mixed leukocyte transformation reaction. In each case, one member of the set had acute leukemia in relapse. In no instance did the leukemic cells of the patient stimulate the cells of the normal twin, nor did cells from the normal twin stimulate cells from the l...

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 1970

ISSN: 0021-9738

DOI: 10.1172/jci106446